Dennis Quaid

Sander

Milo Ventimiglia

Hunter

Brooke Lena Johnson

Ello

Kathleen Rose Perkins

Juliana

Jennifer Tilly

Lucille

Thomas Haden Church

Winstead (voice)

Mary Steenburgen

Claire

Ethan Loomis

Sean

Marissa Jaret Winokur

Nurse Miller

Cathryn Michon

Mrs. O'Brien

W. Bruce Cameron

Peter Altbef

Karen LeBlanc

Allison